The Toronto Star has a nice story, The computer program billed as unbeatable at poker, about a poker playing program Cepehus that was developed at the Computer Poker Research here at the University of Alberta. Michael Bowling is quoted to the effect that,
No matter what you do, no matter how strong a player you are, even if you look at our strategy in every detail . . . there is no way you are going to be able of have any realistic edge on us.
On average we are playing perfectly. And that’s kind of the average that really matters.
You can play Cepehus at their web site. You can read their paper “Heads-up limit hold’em poker is solved”, just published in Science here (DOI: 10.1126/science.1259433).